Abstract
In a blinded, placebo-controlled study, we investigated whether intracoronary infusion of autologous mononuclear cells from granulocyte colony-stimulating factor (G-CSF)-mobilized apheresis product or bone marrow (BM) improved sensitive outcome measures in a swine model of large myocardial infarction (MI).
Publication information
de Silva R, Raval AN, Hadi M, Gildea KM, Bonifacino A, Yu Z, Yau YY, Leitman S, Bacharach SL, Donahue RF, Read EJ, Lederman RJ. Intracoronary infusion of autologous mononuclear cells derived from bone marrow or G-CSF mobilized apheresis product may not improve remodeling, contractile function, perfusion or infarct size in a swine model of large myocardial infarction. Eur Heart J 2008;29:1172-82