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Distinct endotypes of steroid resistant asthma characterized by IL-7A and IFNg immunophenotypes

Abstract

A small population of patients with severe asthma does not respond to glucocorticoids (steroid resistant [SR]). They have high morbidity, highlighting an urgent need for strategies to enhance glucocorticoid responsiveness.


Publication information

Chambers ES, Nanzer AM, Corrigan C, Hawrylowizc CM et al 'Distinct endotypes of steroid resistant asthma characterized by IL-7A and IFNgimmunophenotypes' Journal of Allergy and Clinical Immunology 2015 Sep;136(3):628-637.e4

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